Impact of Prunus Cerasus on PGR and HAS2 in Cumulus Cells and Fertility Outcome

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Impact of Prunus Cerasus on PGR and HAS2 in Cumulus Cells and Fertility Outcome.

PURPOSE Cumulus cells have a critical role in normal oocyte development and fertilization. Prunus cerasus is an anthocyanin rich berry and performs strong antioxidant activity. The present study set to determine if Prunus cerasus can affect expression of HAS2 (hyaluronan synthase 2) and progesterone receptor in Cumulus cells and its consequences outcome of the in vitro fertilization. METHODS ...

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Background: Cherries are an important source of phyto- chemicals, especially anthocyanin. They have many potent biological Properties such as antioxidant activity. Oxidative stress is mainly insert their effect through decreasing of cell proliferation and viability. Infertility problem affect more than 15% of young couples in different societies. Oocyte expansion plays an important role in fert...

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Evaluating The Effect of Melatonin on HAS2 , and PGR Expression, as Well as Cumulus Expansion, and Fertility Potential in Mice

OBJECTIVES Infertility is a worldwide health problem which affects approximately 15% of sexually active couples. One of the factors influencing the fertility is melatonin. Also, protection of oocytes and embryos from oxidative stress inducing chemicals in the culture medium is important. The aim of the present study was to investigate if melatonin could regulate hyaluronan synthase-2 (HAS2) and...

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P-129: Prunus Cerasus Effects on Progesterone Receptor Expression in Cumulus Cells

Background: Infertility is defined as inability to achive pregnancy after one year of unprotected regular intercourse.it has been reported that about 10-15% of young couples suffer from infertility. There is evidence that antioxidants improve the fertility rate. Prunus cerasus contains strong antioxidant activity. The aim of this study is to evaluate Prunus cerasus effects on expression of prog...

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ژورنال

عنوان ژورنال: Advanced Pharmaceutical Bulletin

سال: 2016

ISSN: 2228-5881,2251-7308

DOI: 10.15171/apb.2016.010